Acupuncture, frequently combined with herbal medicine, has been used for centuries to treat some causes of infertility. For example, acupuncture and herbs will not work to address tubal adhesions which can occur as a result of pelvic inflammatory disease or endometriosis. However, in this situation, an individual could still benefit from acupuncture and herbs because of the potential effect of improved ovarian and follicular function. Additionally, it is shown that acupuncture can increase blood flow to the endometrium, helping to facilitate a thick, rich lining.

Acupuncture can be used to treat any type of fertility disorder including spasmed tubes.  Acupuncture is often combined with herbs to treat elevated follicle stimulating hormone (FSH), repeated pregnancy loss, unexplained infertility, luteal phase defect, hyperprolactinemia (when not caused by a prolactinoma), polycystic ovarian syndrome (PCOS) with annovulatory cycles, and male factor including men affected with sperm-DNA-fragmentation.

Patients are commonly treated for three to four months before an insemination, in vitro fertilization (IVF), or donor-egg transfer. This period of treatment seems to have the best therapeutic effect. It is thought that acupuncture stimulates the neurotransmitters that trigger the production of gonadotrophin-releasing hormone, which controls the menstrual cycle and a woman's ovulation. Acupuncture is also thought to stimulate blood flow to the uterus and boost the production of endogenous opioids, inducing the body to relax.